Post-conization HPV testing for predicting recurrence risk!

HPV

In women with high-grade cervical intraepithelial neoplasia (CIN 2,3), positive margins on the cone biopsy specimen are predictive of recurrent high-grade or invasive disease (CIN 2+). However, a recent meta-analysis found that a positive test for high-risk human papillomaviruses (HPV) after excision was a more accurate indicator of treatment failure (sensitivity 91 percent for HPV…

Whats New – Late Literature Review

Uncategorized

Studies reporting on outcomes of histologically confirmed CIN2 in non-pregnant women, managed conservatively for three or more months.  Management of high-grade cervical intraepithelial neoplasia (CIN 2 or 3) has evolved over time, and current guidelines encourage expectant management rather than conization for young women, based on high regression rates. In a meta-analysis including over 3000…