US FDA approves expanded use of Merck’s Gardasil 9 vaccine to include individuals 27 through 45 years old

The US Food and Drug Administration (FDA) approved a supplemental application for Gardasil 9 (Human Papillomavirus (HPV) 9-valent Vaccine, Recombinant) expanding the approved use of the vaccine to include women and men aged 27 through 45 years. Gardasil 9 prevents certain cancers and diseases caused by the nine HPV types covered by the vaccine.

Reasons why the screening programs may not be uniform

We may tend to think of our health-care system as a national program. In reality, the states and territories are responsible for delivering health-care services. That means local authorities are in charge of setting up health programs and sometimes opinions vary about what’s the best approach. As a result, cancer screening can differ from one…

Study Suggests HPV Test More Accurate Than Pap Smear for Cervical Cancer Screening

When it comes to cervical cancer screening, most women receive a cytology-based Papanicolau (Pap) smear, where cells are scraped from the back of the cervix. However, human papillomavirus (HPV)-based testing may be a more accurate way of testing for cervical cancer, new study results suggest.1 Despite the widespread use of cervical cancer screening with a…

Latest Nature Study – Cervical Cancer Revelations

Histologically, CC can be characterized by two different sub-categories i.e. (i) invasive squamous cell carcinomas (ISCC) which are frequent and covers 85–90% of CC cases (ii) adenocarcinomas (ADC) which are relatively rare and comprises only 10–15% cases. The CC develops progression of precancerous lesions; called cervical intraepithelial neoplasia (CIN) grade 1–3 or squamous intraepithelial lesion (SIL).

Post-conization HPV testing for predicting recurrence risk!

In women with high-grade cervical intraepithelial neoplasia (CIN 2,3), positive margins on the cone biopsy specimen are predictive of recurrent high-grade or invasive disease (CIN 2+). However, a recent meta-analysis found that a positive test for high-risk human papillomaviruses (HPV) after excision was a more accurate indicator of treatment failure (sensitivity 91 percent for HPV…