Outcomes and costs of open, robotic, and laparoscopic radical hysterectomy for stage IB1 cervical cancer. MIS is associated with decreased morbidity and costs. However, among women with ≥ 2 cm stage IB1 cervical cancer, MIS was associated with significantly decreased survival.
Background:Surgery is the primary treatment modality for early cervical cancer. Compared to open (ORH), a robotic (RRH) or laparoscopic (LRH) approach to radical hysterectomy may have decreased morbidity, but the influence of surgical approach on survival, specific perioperative complications, and costs is unknown. Methods:The 2010-2013 National Cancer Database (NCDB) was used to evaluate the 5-year survival (5YS) of women with stage IB1 cervical squamous cell carcinoma or adenocarcinoma after radical hysterectomy performed open or by minimally invasive surgery (MIS). Survival times were estimated with the Kaplan-Meier method. Multivariable Cox proportional-hazards model (CPH) was used to adjust for measured confounders. The 2010-2015 Premier Healthcare Database was used to compare complications, length of stay (LOS), readmission rates, and hospitalization costs between ORH, RRH, and LRH. All p-values are two-sided.
Conclusions: MIS is associated with decreased morbidity and costs. However, among women with ≥ 2 cm stage IB1 cervical cancer, MIS was associated with significantly decreased survival.
SOURCE: https://meetinglibrary.asco.org/record/161887/abstract