Post-conization HPV testing for predicting recurrence risk!
In women with high-grade cervical intraepithelial neoplasia (CIN 2,3), positive margins on the cone biopsy specimen are predictive of recurrent high-grade or invasive disease (CIN 2+). However, a recent meta-analysis found that a positive test for high-risk human papillomaviruses (HPV) after excision was a more accurate indicator of treatment failure (sensitivity 91 percent for HPV…