US FDA approves expanded use of Merck’s Gardasil 9 vaccine to include individuals 27 through 45 years old

The US Food and Drug Administration (FDA) approved a supplemental application for Gardasil 9 (Human Papillomavirus (HPV) 9-valent Vaccine, Recombinant) expanding the approved use of the vaccine to include women and men aged 27 through 45 years. Gardasil 9 prevents certain cancers and diseases caused by the nine HPV types covered by the vaccine.

Study Suggests HPV Test More Accurate Than Pap Smear for Cervical Cancer Screening

When it comes to cervical cancer screening, most women receive a cytology-based Papanicolau (Pap) smear, where cells are scraped from the back of the cervix. However, human papillomavirus (HPV)-based testing may be a more accurate way of testing for cervical cancer, new study results suggest.1 Despite the widespread use of cervical cancer screening with a…

Uterine cancers are not “occult” if gynecologists don’t bother to look

:: Noorchashm:: what is not looked for cannot be found??? Is every symptomatic woman over age 55, considered a candidate for complete or partial uterine resection (a.k.a. Hyster-ectomy), should undergo a hysteroscopic endometrial biopsy to directly identify and biopsy any abnormal endometrial tissue present. If an abnormality is found, the woman should undergo an oncological resection—preferably…

Post-conization HPV testing for predicting recurrence risk!

In women with high-grade cervical intraepithelial neoplasia (CIN 2,3), positive margins on the cone biopsy specimen are predictive of recurrent high-grade or invasive disease (CIN 2+). However, a recent meta-analysis found that a positive test for high-risk human papillomaviruses (HPV) after excision was a more accurate indicator of treatment failure (sensitivity 91 percent for HPV…